Overview
This test assists in the diagnosis of autoimmune myasthenia gravis (MG).
Test code: | MuSK RIPA |
Abbreviations: | MuSK Ab; MuSK RIPA |
Methodology | In-house radioimmunoprecipitation assay |
Validation: | Laboratory developed test (LDT) |
Requirements
Specimen type: | Serum |
Minimum volume: | 0.5 mL |
Preferred volume: | 3 mL |
Rejection criteria: | Grossly hemolytic, lipemic, or icteric. If the sample arrives at room temperature. |
Specimen
Specimen collection: | • No patient preparation required before collection. |
Specimen handling: | Centrifuge SST tubes at 1800 - 2200 x g for 10-15 minutes |
Specimen stability: | Serum samples may be stored: |
Performance
Testing frequency: | Once a week (2 day testing procedure) |
Turnaround time: | 2-8 days |
Reference range: | N/A |
Additional Information
- This test was developed and its performance determined by Neurocode USA Inc. It has not been cleared or approved by the Food and Drug Administration.
- Please indicate if patients are on immunomodulating treatments as these may interfere with testing.
- Causal antibodies cannot be identified in about 10% of MG cases. Therefore, a positive result is specific for the diagnosis of AChR ab myasthenia gravis (MG), but a negative result does not rule out an MG diagnosis.