These assays are for the detection of specific nodal and paranodal autoantibodies to assist in the diagnosis of autoimmune nodopathy and differentiate from chronic inflammatory demyelinating polyneuropathy.

Test code:

AN CBA Panel

Abbreviations, alternative names:



In-house fixed cell-based assay


Research use only (RUO)


Specimen type:


Minimum volume:

0.5 mL

Preferred volume:

3 mL

Rejection criteria:

Grossly hemolytic, lipemic, or icteric. If the sample arrives at room temperature.

Our offices are only able to receive samples Mon-Fri, so samples must be shipped Mon-Thur. Samples arriving over the weekend may need to be re-drawn.


Specimen collection:

No patient preparation is required for sample collection.
Draw blood in tube(s) with SST activator (5mL gold top or 8.5mL tiger top).
Invert tubes 8 times to ensure complete mixing.

Specimen handling:

Centrifuge SST tubes at 1800 - 2200 x g for 10-15 minutes
Draw off serum (top layer) into Aliquot tubes with pipette, ensuring not to take gel or RBC (middle/bottom layers)
Store Aliquot tubes in refrigerator (2°C - 8°C) until shipping.

Specimen stability:

Serum samples may be stored:
Up to 1 week refrigerated (2 - 8⁰C)
-20⁰C for longer term storage – avoid subsequent freeze thaws


Testing frequency:

Once every 2 weeks

Turnaround time:

2-3 weeks

Reference range:


Additional Information

  • This test was developed and its performance characteristics determined by BCNI. The test was performed in a DAP, CAP and CLIA certified laboratory and is intended for clinical purposes
  • Please indicate if patients are on immunomodulating treatments as these may interfere with testing.

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