Overview


This test is for the detection of MOG antibodies to assist in the diagnosis of MOGAD.

Test code:

MOG CBA

Abbreviations, alternative names:

MOG Ab, MOGAD CBA

Methodology:

In-house live cell-based assay

Validation:

Laboratory developed test (LDT)

Requirements


Specimen type:

Serum

Minimum volume:

0.3 mL

Preferred volume:

5 mL

Rejection criteria:

Grossly hemolytic, lipemic, or icteric. If the sample arrives at room temperature.

Our offices are only able to receive samples Mon-Fri, so samples must be shipped Mon-Thur. Samples arriving over the weekend may need to be re-drawn.

Specimen


Specimen collection:

No patient preparation is required for sample collection.
Draw blood in tube(s) with SST activator (5mL gold top or 8.5mL tiger top).
Invert tubes 8 times to ensure complete mixing.

Specimen handling:

Centrifuge SST tubes at 1800 - 2200 x g for 10-15 minutes
Draw off serum (top layer) into Aliquot tubes with pipette, ensuring not to take gel or RBC (middle/bottom layers)
Store Aliquot tubes in refrigerator (2°C - 8°C) until shipping.

Specimen stability:

Serum may be stored:
Up to 7 days refrigerated (2 - 8⁰C)
-20⁰C for longer term storage – avoid subsequent freeze thaws

Performance


Testing frequency:

On demand

Turnaround time:

1 week

Reference range:

N/A

Additional Information


  • This test was developed and its performance characteristics determined by BCNI. The test was performed in a DAP, CAP and CLIA certified laboratory and is intended for clinical purposes
  • Please indicate if patients are on immunomodulating treatments as these may interfere with testing.

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